Molecular Imaging: PARP-1 and Beyond
نویسندگان
چکیده
The genetic code to life is balanced on a string of DNA that under constant metabolic and physical stress from environmental forces. Nearly all diseases have component caused by or resulting in damage alters biology drive pathogenesis. Recent advancements repair led the development imaging tools target response proteins. PET has been used for early detection oncogenic processes monitoring tumor chemotherapeutics machinery. In field precision medicine, provide unique opportunity patient stratification directly measuring drug expression therapy identify responders. This overview discusses state art molecular past 5 years, with an emphasis poly[adenosine diphosphate ribose]polymerase-1 as predictive biomarker therapy.
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ژورنال
عنوان ژورنال: The Journal of Nuclear Medicine
سال: 2021
ISSN: ['1535-5667', '0161-5505']
DOI: https://doi.org/10.2967/jnumed.120.243287